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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
19.7
Human Site:
S216
Identified Species:
43.33
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
S216
G
L
S
Q
K
P
I
S
S
F
A
D
F
E
R
Chimpanzee
Pan troglodytes
XP_510910
679
74714
T216
G
L
T
Q
K
P
I
T
S
F
A
D
F
E
R
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
T205
G
L
T
Q
K
P
I
T
S
F
A
D
F
E
R
Dog
Lupus familis
XP_547058
651
71817
H207
S
F
A
D
F
E
R
H
F
L
P
A
S
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
T211
G
L
T
Q
K
P
I
T
S
F
S
D
F
E
Q
Rat
Rattus norvegicus
Q5I0E8
657
73037
T208
G
L
T
Q
K
P
I
T
S
F
S
E
F
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
N207
G
V
T
L
K
T
I
N
S
F
G
D
F
D
E
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
N207
H
F
I
P
A
S
L
N
R
T
T
A
S
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
N206
I
K
V
M
Q
V
G
N
K
N
R
T
V
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
S267
S
A
L
G
N
V
I
S
A
L
V
D
G
K
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
R232
G
A
T
H
V
E
I
R
N
Q
Q
N
F
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
86.6
86.6
0
N.A.
73.3
66.6
N.A.
N.A.
N.A.
46.6
0
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
73.3
20
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
10
0
0
0
10
0
28
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
55
0
10
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
0
10
0
46
19
% E
% Phe:
0
19
0
0
10
0
0
0
10
55
0
0
64
0
10
% F
% Gly:
64
0
0
10
0
0
10
0
0
0
10
0
10
10
0
% G
% His:
10
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
73
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
55
0
0
0
10
0
0
0
0
10
10
% K
% Leu:
0
46
10
10
0
0
10
0
0
19
0
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
28
10
10
0
10
0
0
10
% N
% Pro:
0
0
0
10
0
46
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
46
10
0
0
0
0
10
10
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
10
10
10
0
10
0
0
10
28
% R
% Ser:
19
0
10
0
0
10
0
19
55
0
19
0
19
0
10
% S
% Thr:
0
0
55
0
0
10
0
37
0
10
10
10
0
10
0
% T
% Val:
0
10
10
0
10
19
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _